Bhopal Memorial Hospital and Research Center (BMHRC) has introduced a DNA sequencer to enhance the accuracy of sickle cell anemia testing. This advancement supports the union government’s Sickle Cell Anemia Eradication Mission by enabling precise genetic analysis.
According to BMHRC Director Dr. Manisha Shrivastava, sickle cell anemia is an inherited condition caused by mutations in the HBB gene. While conventional tests identify different hemoglobin types, the DNA sequencer directly examines the HBB gene to detect specific mutations. This allows for more personalized treatment approaches and helps determine suitable gene editing strategies.
By pinpointing the exact genetic mutation, the DNA sequencer plays a vital role in gene editing techniques like CRISPR. It helps identify patients who may benefit most from these therapies, bringing hope for a potential cure for sickle cell anemia in the future.
